Courses and webinars

Chemical probes are indispensable tools in modern biology. These compounds are commonly used to study gene function, validate molecular targets, or dissect complex processes within cells and organisms. Probes’ main attributes reside in their potency, selectivity, and well-defined mechanism of action, yet identifying compounds that meet all the demands of an experimental design is not a trivial task. Information on candidate probes are typically scattered over various sources, and gathering such information can be very time-consuming.

This webinar aims to introduce the main sources/providers of chemical probes along with the criteria to assess their quality. It will also provide an overview of data platforms helpful during their selection process with live demonstrations employing the Probes & Drugs portal (https://www.probes-drugs.org/, developed at the Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic).

Speaker: Ing. Ctibor Škuta, Ph.D. | Cheminformatician CZ-OPENSCREEN: National Infrastructure for Chemical Biology

Date: Wednesday, September 23rd, 2020. 15:00 - 16:15 CET

Registration: The registration will be open from August 24th, 2020.

Costs: This webinar is free-of-charge, but you need to register for a place beforehand.

Dial in: Webex Dial-In will be provided after registration

Contact: sarka.simova@img.cas.cz

Šárka Šímová (IMG, Prague, Czech Republic), Francisca Vicente (Fundación MEDINA, Granada, Spain), Sheraz Gul (IME, Hamburg, Germany) and Jose Manuel Brea (USC, Santiago de Compstela, Spain) presented an Introduction to High-Throughput Screening - Webinar, a web-based theoretical course for researchers and students considering HTS as part of their research.

Webinar program:

• Target identification and definition (hit, lead, drug target), assay development
• Compound collection (desired properties, compound libraries)
• Assay optimization, pilot screen and primary screen Hit selection and confirmation
• Data analysis (detection technologies and data normalization)

   
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